) use. We report two patients with no prior history of neurological condition that knowledgeable their very first generalized tonic–clonic seizure just after using tobacco Spice. The system behind the probable proconvulsant influence of synthetic cannabinoids isn't recognised, but it might be due to their results at the cannabinoid receptor CB1.

) use. We report 2 patients without any prior heritage of neurological ailment that experienced their initially generalized tonic–clonic seizure just after using tobacco Spice. The system powering the achievable proconvulsant effect of artificial cannabinoids just isn't acknowledged, but it might be due to their outcomes at the cannabinoid recept

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